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New patent, WO 2016001885, Dr Reddy’s Laboratories Ltd, Eliglustat hemitartarate
WO 2016001885 DR. REDDY’S LABORATORIES LIMITED [IN/IN]; 8-2-337, Road No. 3, Banjara Hills, Telangana, India Hyderabad 500034 (IN) VELAGA, Dharma Jagannadha Rao; (IN). PEDDY, Vishweshwar; (IN). VYALA,...
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SKLB 1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl,
SKLB 1028 IND Filed A multi-targeted inhibitor potentially for the treatment of leukemia and non small cell lung cancer. SKLB-1028 Si Chuan University, 四川大学 CAS 1350544-93-2...
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Acotiamide
Acotiamide hydrochloride trihydrate CAS#: 773092-05-0 (Acotiamide HCl hydrate, 1:1:3); 185104-11-4(Acotiamide HCl, 1:1); 185106-16-5 (Acotiamide free base) Chemical Formula: C21H37ClN4O8S...
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Ponalrestat
Ponalrestat Phase III An aldose reductase inhibitor potentially for the treatment of diabetes. Imperial Chemical Industries Limited innovator ICI-128436; MK-538; ICI-plc CAS No.72702-95-5 Statil;...
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VAL-083
VAL-083 (1R,2S)-1-((R)-oxiran-2-yl)-2-((S)-oxiran-2-yl)ethane-1,2-diol Galactitol, 1,2:5,6-dianhydro- 1,2:5,6-Dianhydrodulcitol 1,2:5,6-Dianhydrogalactitol 1,2:5,6-Diepoxydulcitol...
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Aliskiren
ALISKIREN (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide, CAS 173334-57-1, base CAS...
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AT 9283
AT9283, AT 9283 N-cyclopropyl-N’-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea...
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Breaking and Making of Olefins Simultaneously Using Ozonolysis: Application...
A simple and practical one-pot, two-directional approach to access olefinic esters through simultaneous breaking and making of olefins using ozonolysis of alkenyl aryl selenides is disclosed. The...
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Lupin Ltd, Patent, Pitavastatin, WO2014203045
Lupin Ltd, Patent, Pitavastatin, WO2014203045 A NOVEL, GREEN AND COST EFFECTIVE PROCESS FOR SYNTHESIS OF TERT-BUTYL (3R,5S)-6-OXO-3,5-DIHYDROXY-3,5-O-ISOPROPYLIDENE-HEXANOATE ROY, Bhairabnath; (IN)....
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FDA´s Emerging Technology Applications Program – Draft Guidance
FDA´s Emerging Technology Applications Program – Draft Guidance The FDA recently published a draft guidance for industry on the “Advancement of Emerging Technology Applications”. The draft guidance...
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What was the drug in Clinical Trial Tragedy In France Jan 2016
BIA 10-2474 3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide Bial-Portela & Ca. S.A. BIA 10-2474 is an experimental fatty acid amide hydrolase inhibitor[1] developed by the...
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Fresolimumab
Fresolimumab GC 1008, GC1008 UNII-375142VBIA cas 948564-73-6 Structure immunoglobulin G4, anti-(human transforming growth factors beta-1, beta-2 (G-TSF or cetermin) and beta-3), human monoclonal...
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5-Bromo-1-methyl-1H-imidazole-4-carbonitrile
Source: 5-Bromo-1-methyl-1H-imidazole-4-carbonitrileFiled under: Uncategorized
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New TRPV1 Antagonist From Neurogen Corporation
MK ? NGD? MK 2295; NGD 8243 may be??????? CAS 878811-00-8 FREE FORM Molecular Formula: C27H31FN6O2 Molecular Weight: 490.572443 g/mol...
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PF 04995274, a 5-HT4Partial Agonist
PF-04995274, (R)-4-((4-(((4-(Tetrahydrofuran-3-yloxy)-1,2-benzisoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol...
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New Website ECA Validation Group: Version 02 of ECA´s Good Practice Guide on...
The ECA Validation Group was founded in autumn 2011 by representatives of the pharmaceutical industry after ECA´s 4th European GMP Conference. The mission of the group is to assemble knowledge on...
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Talazoparib, BMN 673
Talazoparib, BMN-673, MDV-3800 (2S,3S)-methyl-7-fluoro-2-(4-fluorophenyl)-3-(1-methyl-1H-1,2,4-triazol-5-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate...
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VASICINE, (peganine)
. Vasicine (peganine) is a quinazoline alkaloid. It is the active compound of Justicia adhatoda, after which the chemical is named. Vasicine has been compared to theophylline both in vitro and in...
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NIZATIDINE
Nizatidine is a histamine H2 receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux...
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