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CFG 920, Novartis Scientists team up with Researchers at Aurigene, Bangalore,...
CFG920, Inhibitor Of Prostate Cancer With Fewer Cardiac Side Effects Cas 1260006-20-9 Novartis Target: CYP17/CYP11B2 Disease: Castration-resistant prostate cancer MF C14H13ClN4O MW: 288.0778 Elemental...
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GDC-0919; NLG-919; RG-6078
MF C18H22N2O MW: 282.17321 GDC-0919; NLG-919; RG-6078, GDC0919; GDC-0919; GDC 0919; NLG919; NLG 919; NLG-919; RG6078; RG-6078; RG 6078. 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol CAS...
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ICH Q3D implemented in the European Pharmacopoeia: Revision of Two General...
DRUG REGULATORY AFFAIRS INTERNATIONAL ICH Q3D implemented in the European Pharmacopoeia: Revision of Two General Monographs with Regard to Elemental Impurities Two general monographs of the European...
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The new Annex 16 “Certification by a Qualified Person and Batch Release” will...
DRUG REGULATORY AFFAIRS INTERNATIONAL The new Annex 16 is coming into Force The new Annex 16 “Certification by a Qualified Person and Batch Release” will become effective as of 15 April 2016. The...
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GDC-0084
GDC-0084 CAS#: 1382979-44-3 Chemical Formula: C18H22N8O2 Exact Mass: 382.1866 Synonym: RG7666; RG-7666; RG 7666; GDC-0084; GDC0084; GDC 0084. IUPAC/Chemical Name:...
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Debiopharm and Aurigene dual c-src / jak inhibitors
Debio 1142 Jak2 tyrosine kinase inhibitor; Src tyrosine kinase inhibitor...
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CN-128 for the treatment of thelassemia and iron overload
CN-128 (R)-3-Hydroxy-1-(1-hydroxy-3-benzyl propyl-2-)2-methyl pyridine-4(1H)-one IND Filing CN-128 is potentially for the treatment of thelassemia and iron overload. Zhejiang University, 浙江大学 CAS No....
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ND 2158
(2S)-2-hydroxy-3-[(3R)-12-{[(1r,4r)-4-(morpholin-4-yl)cyclohexyl]oxy}-7-thia-9,11-diazatricyclo[6.4.0.0²,⁶]dodeca-1(12),2(6),8,10-tetraen-3-yl]propanamide...
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Curis and Aurigene’s AUPM 170, CA 170
1,2,4-oxadiazole and 1 ,2,4-thiadiazole compounds of formula (I): ONE EXAMPLE OR 1,3,4-oxadiazole and 1 ,3,4-thiadiazole compounds of formula (I): EXAMPLES PREDICTED AUPM 170, CA 170, AUPM-170, CA-170...
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Curis and Aurigene’s CA 4948, AU 4948
Example 13 WO2015104688 6-(6-aminopyridin-3-yl)-N-(2-morpholin-4-yl-1,3-benzothiazol-6-yl)pyridine-2-carboxamide Molecular Formula: C22H20N6O2S Molecular Weight: 432.4982 g/mol 1428335-77-6...
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PF-05387552
PF-05387552 IRAK4 CAS 1604034-71-0 C25 H27 N5 O2 11H-Indolo[3,2-c]quinoline-9-carbonitrile, 2-methoxy-3-[3-(4-methyl-1-piperazinyl)propoxy]-...
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ATR 101
N-(2,6-bis(1-methylethyl)phenyl)-N’-((1-(4-(dimethylamino)phenyl)cyclopentyl) methyl)urea hydrochloride N-(2,6-BIS(l-METHYLETHYL)PHENYL)-N’-((l-(4- (DIMETHYLAMINO)PHENYL)CYCLOPENTYL)METHYL)UREA...
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AMG 337
. PIC CREDIT.BETHANY HALFORD Name: AMG-337(AMG337; AMG 337) Cas 1173699-31-4 Formula: C23H22FN7O3 M.Wt: 463.46 Chemical Name:...
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ND 0126
ND 0126 CAS 1240322-54-6 Molecular Formula: C29H25F3N6O3 Molecular Weight: 562.54241 g/mol methyl...
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PF-06260414
PF-06260414 CAS: 1612755-71-1 Chemical Formula: C14H14N4O2S Exact Mass: 302.0837 PF-06260414; PF 06260414; PF06260414; PF6260414; PF-6260414; PF 6260414. IUPAC/Chemical Name:...
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Enasidenib (AG-221)
Enasidenib (AG-221) 1446502-11-9 Chemical Formula: C19H17F6N7O Exact Mass: 473.13988 AG-221; AG 221; AG221; CC-90007; CC 90007; CC90007; Enasidenib IUPAC/Chemical Name:...
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Regulatory Approval Pathways: EU vs US
DRUG REGULATORY AFFAIRS INTERNATIONAL Regulatory Approval Pathways: EU vs US Drug Authorization Procedures in the EU Sponsors have several options when seeking market approval for a new drug in...
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1R,2S-Methoxamine
1R,2S-methoxamine, also known as L-erythro-methoxamine CAS 13699-29-1 Benzenemethanol, α-[(1S)-1-aminoethyl]-2,5-dimethoxy-, (αR)- Benzenemethanol, α-(1-aminoethyl)-2,5-dimethoxy-, [R-(R*,S*)]-...
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GMP/GDP: When will I be inspected by the Authorities?
DRUG REGULATORY AFFAIRS INTERNATIONAL Various competent authorities are performing inspections. But who is subject to such an inspection?...
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