Clik here to view.
Genistein
Genistein 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4’,5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol; CAS Number: 446-72-0...
View ArticleClik here to view.
Temanogrel
Temanogrel APD 791 3-methoxy-N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholinoethoxy)phenyl]benzamide Benzamide,3-methoxy-N-[3-(1-methyl-1H-pyrazol-5-yl)-4-[2-(4-morpholinyl)ethoxy]phenyl]- UNII:F42Z27575A...
View ArticleClik here to view.
TD 1607
TD-1607 Phase I A glycopeptide-cephalosporin heterodimer potentially for the treatment of gram-positive bacterial infection. CAS No. 827040-07-3 C95 H109 Cl3 N18 O31 S2, Molecular Weight, 2169.47...
View ArticleClik here to view.
Clik here to view.
GSK-2816126
GSK-2816126 N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide, GSK 126, GSK 2816126, GSK 2816126A...
View ArticleClik here to view.
GSK-2879552
GSK-2879552 CAS 1401966-69-5 (ABS), 1401966-63-9(REL) C23 H28 N2 O2, 364.48 Benzoic acid, 4-[[4-[[[(1R,2S)-2-phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]-...
View ArticleClik here to view.
GSK-2881078
GSK-2881078 (R)-1-[1-(Methylsulfonyl)propan-2-yl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile (R)-1 -(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)indoline-5-carbonitrile Phase I A selective...
View ArticleClik here to view.
Amneal Pharma’s, 4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing...
Cas 1580464-40-9 MW458.97, C24 H19 Cl N6 S, 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 4-(4-chlorophenyl)-4,7-dihydro-3-methyl-1-(10H-phenothiazin-2-yl)-...
View ArticleClik here to view.
Indian API Manufacturers remain in the Focus of European GMP Inspectors
DRUG REGULATORY AFFAIRS INTERNATIONAL Some time ago three Non-Compliance Reports have been published in quick succession in the EudraGMDP database. Those reports deal with inspections performed at...
View ArticleClik here to view.
Revision of the general Chapter on Pharmaceutical Water in the US Pharmacopoeia
DRUG REGULATORY AFFAIRS INTERNATIONAL The 2nd supplement of USP39 NF34 comprises the revised version of the chapter on pharmaceutical water of the US Pharmacopoeia <1231> Water for...
View ArticleClik here to view.
Final WHO Guidance Document on Good Data and Record Management Practices
DRUG REGULATORY AFFAIRS INTERNATIONAL The WHO has just released the the final version of the important guideline “Good Data and Record Management Practices“....
View ArticleClik here to view.
Novartis, Torrent drug for diabetes, NVP-LBX192, LBX-192
(R)-3-Cyclopentyl-N-(5-methoxy-thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methyl-piperazine-1-sulfonyl)-phenyl]-propionamide...
View ArticleClik here to view.
FDA publishes Technical Guide on Quality Metrics
DRUG REGULATORY AFFAIRS INTERNATIONAL The FDA has published a supplementing Guide on Quality Metrics. This is a very unusual step as the contents of the guide are planned to be integrated into the...
View ArticleClik here to view.
Annex 16: How a QP should handle unexpected Deviations
DRUG REGULATORY AFFAIRS INTERNATIONAL In a recent blog of the MHRA, the inspectorate looks at one aspect of the new Annex 16 – the handling of unexpected deviations. see...
View ArticleClik here to view.
Ripasudil hydrochloride hydrate 塩酸塩水和物 , リパスジル
Ripasudil hydrochloride hydrate 4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline;dihydrate;hydrochloride 4-Fluoro-5-[2(S)-methylperhydro-1,4-diazepin-1-ylsulfonyl]isoquinoline...
View ArticleClik here to view.
BRISTOL-MYERS SQUIBB’S TRICYCLOHEXADECAHEXAENE DERIVATIVES FOR USE IN THE...
. TRICYCLOHEXADECAHEXAENE DERIVATIVES FOR USE IN THE TREATMENT OF HEPATITIS C VIRUS CAS 1663477-91-5 C54 H62 F4 N6 O2, 903.10 Cyclohexanecarboxamide,...
View ArticleClik here to view.
MK 8876
MK 8876 CAS 1426960-33-9 2-(4-Fluorophenyl)-5-(11-fluoro-6H-pyrido[2′,3′:5,6][1,3]oxazino[3,4-a]indol-2-yl)-N-methyl-6-(N-methylmethanesulfonamido)-1-benzofuran-3-carboxamide...
View ArticleClik here to view.
Clik here to view.
New bicalutamide/enzalutamide derivatives as antiproliferative agents for the...
3,3,3-trifluoro-2-hydroxy-N-(4-nitro-3-(trifluoromethyl)phenyl)-2-(((2-(trifluoromethyl)phenyl)thio)methyl)propanamide Cas 1929605-82-2 MF C18 H11 F9 N2 O4 S, MW 522.34 New bicalutamide and...
View ArticleClik here to view.
EMA reviews Medicines manufactured at U.S. Company
DRUG REGULATORY AFFAIRS INTERNATIONAL Following the issuance of two Non-Compliance Reports for two sites of the US based company, EMA has started a review of medicines manufactured by Pharmaceutics...
View Article